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From TpsWiki

Welcome to the wiki pages of the INFN-TPS Project: a INFN (Istituto Nazionale di Fisica Nucleare) dedicated research project for the development of an innovative TPS (Treatment Planning System) for hadrontherapy.

Contents 1 The Project 2 Research Tasks 3 Main Documentation 4 Wiki Administrators 5 External Links (related to the TPS Project) 6 External Links

The Project

Clinical results obtained with hadrontherapy have been extremely positive for various tumors, with percentages of local control and survival higher than those ascribed to conventional radiotherapy. Most clinical data obtained with these particles are related to protontherapy (about 55000 at the end of 2008) but the implementation of carbon ion therapy has demonstrated to be of great interest in the last decade. These results, accompanied by the new performances in accelerator technology and calculation systems of the delivered dose, have determined over the past years an increased interest for the development of hadrontherapy, with the construction of new centers provided with equipment entirely dedicated to clinical activity (LLUMC, Loma Linda and NPTC, Boston in USA; HIMAC-NIRS, Chiba, PROBEAT, Tsukuba, and Hyogo Beam Medical Centers in Japan; Heavy Ion Therapy Centre at Heidelberg, the Italian National Centre for Oncological Hadrontherapy, CNAO, at Pavia, Geisse-Marburg in Germany andthe French National Hadrontheroay Centre, ETOILE, in Europe).

One of the most important issues in this field is the design of new and advanced Treatment Planning Systems (TPS). In short the TPS is a set of tools that allow the translation of the dose prescription into a set of beam energies, positions and intensities needed for the treatment. Innovative contribution in this field is particularly needed in case of the use of nuclear (ions) projectiles.

Research Tasks

The development and finalization of a TPS require expertises from several research fields. The INFN groups, participating in the present project, have been working on several topics concerning the overall task. The project is subdivided in several research packages:

• Nuclear fragmentation study and measurements.
• Radiobiological modeling and measurements.
• Treatment plan calculation and optimization.
• Monte Carlo developments for treatment planning.
• Online treatment monitoring using in-beam PET.

Here are the members participating to the INFN-TPS Project.

Main Documentation

Here are the links to the main document categories of the TPS project:

• The INFN-TPS Proposal.
• Publications
• Presentations
• Theses

It exists also a semi-private blog dedicated to the project.

Wiki Administrators

• Faiza Bourhaleb
• Andrea Attili

External Links (related to the TPS Project)

• LNF-TPS, TPS home page @ Laboratori Nazionali di Frascati (LNF)

External Links

• Il Buco nero, Sito dei lavoratori precari INFN
• INFN-TPS Blog, the Blog dedicated to the INFN-TPS project
• INFN web-site
• LNF, web site of the INFN's Laboratori Nazionali di Frascati
• LNL, web site of the INFN's Laboratori Nazionali di Legnaro
• LNS, web site of the INFN's Laboratori Nazionali del Sud
• LNGS, web site of the INFN's Laboratori Nazionali del Gran Sasso
• Asimmetrie, official magazine of the INFN
• ScienzaPerTutti, Scientific divulgation @ LNF
• Gruppo Collegato Sanità presso l'Istituto Superiore di Sanità